By Angela Dillow, Anthony Lowman
Provides the way to boost man made and organic fabrics with stronger in vivo homes. Considers the impression of topographical positive factors on mobile behaviors reminiscent of orientation, adhesion, migration, proliferation, and differentiation.
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Additional resources for Biomimetic Materials And Design: Biointerfacial Strategies, Tissue Engineering And Targeted Drug Delivery
Structure) that modify a5 b1 binding and signaling and modulate cell proliferation and differentiation (51). We have examined changes in FN structure upon adsorption onto three commonly used surfaces: hydrophobic (untreated) bacteriological polystyrene, tissue culture-treated polystyrene, and type I collagen-coated polystyrene (FN binds to type I collagen). The conformation of adsorbed FN was examined in an antibody binding assay using monoclonal antibodies directed against speciﬁc structural epitopes in FN (51).
Cancer Commun 1(1):55–63, 1989. 29. W Dai, J Belt, WM Saltzman. Cell-binding peptides conjugated to poly(ethylene glycol) promote cell aggregation. Biotechnology (NY) 12(8):797–801, 1994. 30. K Kawasaki, M Namikawa, Y Yamashiro, Y Iwai, T Hama, Y Tsutsumi, S Yamamoto, S Nakagawa, T Mayumi. Amino acids and peptides. XXV. Preparation of ﬁbronectin-related peptide poly(ethylene glycol) hybrids and their inhibitory effect on experimental metastasis. Chem Pharm Bull (Tokyo) 43(12):133–138, 1995. 31.
63. VS Mangipudi, M Tirrell. Contact-mechanics-based studies of adhesion between polymers. Rubber Chem Technol 71:407–448, 1998. 64. MK Chaudhury, GM Whitesides. Direct measurement of interfacial interactions between semispherical lenses and ﬂat sheets of poly(dimethylsiloxane) and their chemical derivatives. Langmuir 7:1013–1025, 1991. 65. DA Hammer, M Tirrell. Biological adhesion at interfaces. Annu Rev Mater Sci 26:651–691, 1996. 66. Personal communication. © 2002 by Marcel Dekker, Inc. 2 Engineering of Integrin-Speciﬁc Biomimetic Surfaces to Control Cell Adhesion and Function Andre´s J.
Biomimetic Materials And Design: Biointerfacial Strategies, Tissue Engineering And Targeted Drug Delivery by Angela Dillow, Anthony Lowman