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Mark R. Marten, Tai Hyun Park, and Teruyuki Nagamune (Eds.)'s Biological Systems Engineering PDF

By Mark R. Marten, Tai Hyun Park, and Teruyuki Nagamune (Eds.)

ISBN-10: 0841219311

ISBN-13: 9780841219311

ISBN-10: 0841237964

ISBN-13: 9780841237964

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Ch004 The flux amplification factors is calculated from the information of determined FCCs and enzyme amplification factors as (14) i-c; From the determined flux amplification factors, it is predicted how flux will be changed when the new genetic modification is introduced in the metabolic pathway. Results and Discussion Metabolic Flux Analysis by The Constructed M R Model The M R model shown in Table II and eq. (1) was constructed, and consistency of the model was checked by using the consistency index.

8. Edwards, J. ; Schilling, C. ; Palsson, B. O. In Metabolic engineering; Lee, S. ; Papoutsakis, E. ; Marcel Dekker: N Y , 1999, pp 13-57. 9. Bailey, J. E. Science 1991, 252, 1668-1674. 10. Neijssel, O. M . ; de Mattos, M . ; Tempest, D. W. In Escherichia coli and Salmonella; Neidhardt, F. ; A S M press: W A , 1996, pp 1683-1692. 11. Millard, C. ; Chao, Y . ; Liao, J. ; Donnelly, M . I. Appl. Environ. Microbiol. 1996, 62, 1808-1810. 12. Flores, C. ; Gancedo, C. FEBS Lett. 1997, 412(3), 531-534.

W. Wiechert, D . Kownatzki and A . A . de Graaf, Bidirectional Reaction Steps in Metabolic Networks: IV. Optimal Design of Isotopomer Labeling Experiments, Biotechnol. , 60, 86-103 (1999). ,1,282-290(1999). Nielsen, Metabolic network analysis of P. chrisogenum using C-labeled glucose, Biotechnol. , 68, 652-659 (2000). Biosci. , 93,78-87 (2002). [46]Seressiotis, A . E. ; ACS Symposium Series; American Chemical Society: Washington, DC, 2002. ch002 26 System for the Analysis and Synthesis of Metabolic Pathways, Biotechnol.

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Biological Systems Engineering by Mark R. Marten, Tai Hyun Park, and Teruyuki Nagamune (Eds.)

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